On and off sublaminae in the lateral geniculate nucleus of the ferret.
نویسندگان
چکیده
Like the retinal ganglion cells from which they receive their input, most relay neurons in the lateral geniculate nucleus have ON- or OFF-center receptive fields with antagonistic surrounds. In the cat, neurons with these two types of receptive fields are anatomically intermingled, even though the ON and OFF systems are functionally segregated. In the ferret, there is a sublamination of the retinal input to lateral geniculate nucleus laminae A and A1. We have investigated the function of this sublamination by making microelectrode recordings and have found that each sublamina consists of geniculate neurons of a single center type.
منابع مشابه
The neuronal form of nitric oxide synthase is required for pattern formation by retinal afferents in the ferret lateral geniculate nucleus.
The ferret retinogeniculate projection undergoes activity-dependent refinement of connections that become restricted to eye specific laminae and On/Off sublaminae in the lateral geniculate nucleus (LGN). We have previously shown that the developmental process by which On/Off sublaminae form requires N-methyl-D-aspartate (NMDA) receptors and nitric oxide (NO). In this study, we investigate the r...
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The ferret retinogeniculate projection is organized into on/off sublaminae within each eye-specific layer. The role of afferent activity in the formation of these sublaminae was examined. We report that when the activity of retinal ganglion cells is blocked with tetrodotoxin during postnatal weeks three and four, on/off sublamination is disrupted, supporting a role for afferent activity in the ...
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In the retinogeniculate pathway of the ferret, in addition to the separation of the inputs from the two eyes to form eye-specific layers, there is also an anatomical segregation of the terminal arbors of on-center retinal ganglion cells from the terminal arbors of off-center retinal ganglion cell axons to form on/off sublaminae. Sublamination normally occurs during postnatal weeks 3-4 and requi...
متن کاملThe Journal of Comparatiit Neurology
The lateral geniculate nucleus of the ferret contains not only eye-specific layers, but a further subdivision of layers A and A1 into inner and outer sublaminae that contain, respectively, ON-center and OFF-center cells (Stryker and Zahs, '83). To study how the arbors of single retinal ganglion cell axons correlate with these cellular divisions, we have examined the morphology of physiologicall...
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Retinogeniculate projections in the ferret are refined during postnatal development so that inputs from the two eyes become segregated into eye-specific laminae, and each eye-specific lamina is further divided into sublaminae containing inputs from on-center or off-center afferents. Segregation into eye-specific laminae and on/off sublaminae is dependent on neuronal activity; sublamination depe...
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عنوان ژورنال:
- The Journal of neuroscience : the official journal of the Society for Neuroscience
دوره 3 10 شماره
صفحات -
تاریخ انتشار 1983